Bernardes, Goncalo J. L.: search on Z-Library

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1

Machine learning for target discovery in drug development

Rodrigues, Tiago, Bernardes, Gonçalo J.L.

Journal:

Current Opinion in Chemical Biology

Year:

2020

Language:

english

File:

PDF, 995 KB

english, 2020

2

A “Tag-and-Modify” Approach to Site-Selective Protein Modification

Chalker, Justin M., Bernardes, Gonçalo J. L., Davis, Benjamin G.

Journal:

Accounts of Chemical Research

Year:

2011

Language:

english

File:

PDF, 5.47 MB

english, 2011

3

Sulfur-Limonene Polysulfide: A Material Synthesized Entirely from Industrial By-Products and Its Use in Removing Toxic Metals from Water and Soil

Crockett, Michael P., Evans, Austin M., Worthington, Max J. H., Albuquerque, Inês S., Slattery, Ashley D., Gibson, Christopher T., Campbell, Jonathan A., Lewis, David A., Bernardes, Gonçalo J. L., Cha

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 2.65 MB

english, 2016

4

Site-selective protein-modification chemistry for basic biology and drug development

Krall, Nikolaus, da Cruz, Filipa P., Boutureira, Omar, Bernardes, Gonçalo J. L.

Journal:

Nature Chemistry

Year:

2015

Language:

english

File:

PDF, 1.85 MB

english, 2015

5

Enhanced permeability and binding activity of isobutylene-grafted peptides

Sun, Shuang, Compañón, Ismael, Martínez-Sáez, Nuria, Seixas, João D., Boutureira, Omar, Corzana, Francisco, Bernardes, Gonçalo J. L.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.28 MB

english, 2017

6

Site-selective installation of an electrophilic handle on proteins for bioconjugation

Lee, Bernadette, Sun, Shuang, Jiménez-Moreno, Ester, Neves, André A., Bernardes, Gonçalo J.L.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 718 KB

english, 2018

7

The liberating role of conflict in group creativity: A study in two countries

Charlan J. Nemeth, Bernard Personnaz, Marie Personnaz, Jack A. Goncalo

Journal:

European Journal of Social Psychology

Year:

2004

Language:

english

File:

PDF, 104 KB

english, 2004

8

Contemporary approaches to site-selective protein modification

Hoyt, Emily A., Cal, Pedro M. S. D., Oliveira, Bruno L., Bernardes, Gonçalo J. L.

Journal:

Nature Reviews Chemistry

Year:

2019

Language:

english

File:

PDF, 2.82 MB

english, 2019

9

Chemical Modification of Proteins at Cysteine: Opportunities in Chemistry and Biology

Justin M. Chalker, Gonçalo J. L. Bernardes, Yuya A. Lin, Benjamin G. Davis

Journal:

Chemistry – An Asian Journal

Year:

2009

Language:

english

File:

PDF, 1.47 MB

english, 2009

10

Natural product modulators of transient receptor potential (TRP) channels as potential anti-cancer agents

Rodrigues, Tiago, Sieglitz, Florian, Bernardes, Gonçalo J. L.

Journal:

Chemical Society Reviews

Year:

2016

Language:

english

File:

PDF, 2.30 MB

english, 2016

11

o -Boronato- and o -Trifluoroborato–Phosphonium Salts Supported by l -α-Amino Acid Side Chain

Bernard, Julie, Malacea-Kabbara, Raluca, Clemente, Gonçalo S., Burke, Benjamin P., Eymin, Marie-Joëlle, Archibald, Stephen J., Jugé, Sylvain

Journal:

Journal of Organic Chemistry

Year:

2015

Language:

english

File:

PDF, 781 KB

english, 2015

12

Intrinsic Resistance of Burkholderia cepacia Complex to Benzalkonium Chloride

Ahn, Youngbeom, Kim, Jeong Myeong, Kweon, Ohgew, Kim, Seong-Jae, Jones, Richard C., Woodling, Kellie, Gamboa da Costa, Gonçalo, LiPuma, John J., Hussong, David, Marasa, Bernard S., Cerniglia, Carl E.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.00 MB

english, 2016

13

A brain-sparing diphtheria toxin for chemical genetic ablation of peripheral cell lineages

Pereira, Mafalda M. A., Mahú, Inês, Seixas, Elsa, Martinéz-Sánchez, Noelia, Kubasova, Nadiya, Pirzgalska, Roksana M, Cohen, Paul, Dietrich, Marcelo O, López, Miguel, Bernardes, Gonçalo J. L., Domingos

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 855 KB

english, 2017

14

A silicon-labelled amino acid suitable for late-stage fluorination and unexpected oxidative cleavage reactions in the preparation of a key intermediate in the Strecker synthesis

Scroggie, Kymberley R., Alcock, Lisa J., Matos, Maria J., Bernardes, Gonçalo J. L., Perkins, Michael V., Chalker, Justin M.

Journal:

Peptide Science

Year:

2018

Language:

english

File:

PDF, 795 KB

english, 2018

15

Fast-Mover Advantages: Speed Capabilities and Entry into the Emerging Submarket of Atlantic Basin LNG

Hawk, Ashton, Pacheco-de-Almeida, Gonçalo, Yeung, Bernard Yin

Journal:

SSRN Electronic Journal

Year:

2012

Language:

english

File:

PDF, 183 KB

english, 2012

16

A Coordinated Synthesis and Conjugation Strategy for the Preparation of Homogeneous Glycoconjugate Vaccine Candidates

Dr. Elizabeth J. Grayson, Dr. Gonçalo J. L. Bernardes, Justin M. Chalker, Dr. Omar Boutureira, Dr. Julia R. Koeppe, Prof. Benjamin G. Davis

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 672 KB

english, 2011

17

ChemInform Abstract: Developing Drug Molecules for Therapy with Carbon Monoxide

Carlos C. Romao, Walter A. Blaettler, Joao D. Seixas, Goncalo J. L. Bernardes

Journal:

Year:

2012

File:

PDF, 18 KB

2012

18

ChemInform Abstract: Construction of Homogeneous Antibody-Drug Conjugates Using Site-Selective Protein Chemistry

Akkapeddi, Padma, Azizi, Saara-Anne, Freedy, Allyson M., Cal, Pedro M. S. D., Gois, Pedro M. P., Bernardes, Goncalo J. L.

Journal:

Year:

2016

File:

PDF, 16 KB

2016

19

Frontispiece: Site-Selective Modification of Proteins with Oxetanes

Boutureira, Omar, Martínez-Sáez, Nuria, Brindle, Kevin M., Neves, André A., Corzana, Francisco, Bernardes, Gonçalo J. L.

Journal:

Chemistry - A European Journal

Year:

2017

File:

PDF, 761 KB

2017

20

Gastric antral vascular ectasia (GAVE) and hereditary hemorrhagic telangiectasia (HHT): two different conditions, one treatment

Santos, Sara, Bernardes, Carlos, Borges, Verónica, Ramos, Gonçalo

Journal:

Annals of Hematology

Year:

2019

File:

PDF, 320 KB

2019

21

Fast-mover advantages: Speed capabilities and entry into the emerging submarket of atlantic basin LNG

Hawk, Ashton, Pacheco-De-Almeida, Gonçalo, Yeung, Bernard

Journal:

Strategic Management Journal

Year:

2013

Language:

english

File:

PDF, 331 KB

english, 2013

22

Ein niedermolekulares Ligand-Wirkstoff-Konjugat zur Behandlung von Carboanhydrase IX exprimierenden Tumoren

Krall, Nikolaus, Pretto, Francesca, Decurtins, Willy, Bernardes, Gonçalo J. L., Supuran, Claudiu T., Neri, Dario

Journal:

Angewandte Chemie

Year:

2014

Language:

german

File:

PDF, 2.19 MB

german, 2014

23

Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells

Jiménez-Moreno, Ester, Guo, Zijian, Oliveira, Bruno L., Albuquerque, Inês S., Kitowski, Annabel, Guerreiro, Ana, Boutureira, Omar, Rodrigues, Tiago, Jiménez-Osés, Gonzalo, Bernardes, Gonçalo J. L.

Journal:

Angewandte Chemie International Edition

Year:

2017

Language:

english

File:

PDF, 1.33 MB

english, 2017

24

Radical-Mediated Thiol-Ene Strategy: Photoactivation of Thiol-Containing Drugs in Cancer Cells

Sun, Shuang, Oliveira, Bruno L., Jiménez-Osés, Gonzalo, Bernardes, Gonçalo J. L.

Journal:

Angewandte Chemie

Year:

2018

Language:

english

File:

PDF, 1.15 MB

english, 2018

25

Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents

Bernardim, Barbara, Matos, Maria J., Ferhati, Xhenti, Compañón, Ismael, Guerreiro, Ana, Akkapeddi, Padma, Burtoloso, Antonio C. B., Jiménez-Osés, Gonzalo, Corzana, Francisco, Bernardes, Gonçalo J. L.

Journal:

Nature Protocols

Year:

2018

Language:

english

File:

PDF, 1.33 MB

english, 2018

26

Generation of Carbon Monoxide Releasing Molecules (CO-RMs) as Drug Candidates for the Treatment of Acute Liver Injury: Targeting of CO-RMs to the Liver

Marques, Ana R., Kromer, Lukas, Gallo, David J., Penacho, Nuno, Rodrigues, Sandra S., Seixas, João D., Bernardes, Gonçalo J. L., Reis, Patrícia M., Otterbein, Sherrie L., Ruggieri, Rachel A., Gonçalve

Journal:

Organometallics

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012

27

Design, synthesis and biological evaluation of carbohydrate-functionalized cyclodextrins and liposomes for hepatocyte-specific targeting

Bernardes, Gonçalo J. L., Kikkeri, Raghavendra, Maglinao, Maha, Laurino, Paola, Collot, Mayeul, Hong, Sung You, Lepenies, Bernd, Seeberger, Peter H.

Journal:

Organic & Biomolecular Chemistry

Year:

2010

Language:

english

File:

PDF, 507 KB

english, 2010

28

Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation

Lira-Navarrete, Erandi, de las Rivas, Matilde, Compañón, Ismael, Pallarés, María Carmen, Kong, Yun, Iglesias-Fernández, Javier, Bernardes, Gonçalo J. L., Peregrina, Jesús M., Rovira, Carme, Bernadó, P

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 2.49 MB

english, 2015

29

Site-Selective Modification of Proteins with Oxetanes

Boutureira, Omar, Martínez-Sáez, Nuria, Brindle, Kevin M., Neves, André A., Corzana, Francisco, Bernardes, Gonçalo J. L.

Journal:

Chemistry - A European Journal

Year:

2017

Language:

english

File:

PDF, 1.26 MB

english, 2017

30

Towards large-scale three-dimensional blood flow simulations in realistic geometries

Caldini-Queiros, Céline, Chabannes, Vincent, Ismail, Mourad, Pena, Goncalo, Prud’homme, Christophe, Szopos, Marcela, Tarabay, Ranine, Descombes, Stéphane, Dussoubs, Bernard, Faure, Sylvain, Gouarin, L

Journal:

ESAIM Proceedings

Year:

2013

Language:

english

File:

PDF, 1.73 MB

english, 2013

31

Nickel-Catalyzed Azide–Alkyne Cycloaddition to Access 1,5-Disubstituted 1,2,3-Triazoles in Air and Water

Kim, Woo Gyum, Kang, Mi Eun, Lee, Jae Bin, Jeon, Min Ho, Lee, Sungmin, Lee, Jungha, Choi, Bongseo, Cal, Pedro M. S. D., Kang, Sebyung, Kee, Jung-Min, Bernardes, Gonçalo J.L., Rohde, Jan-Uwe, Choe, Won

Journal:

Journal of the American Chemical Society

Year:

2017

Language:

english

File:

PDF, 500 KB

english, 2017

32

Proteome‐wide survey of cysteine oxidation using a norbornene probe

Alcock, Lisa J., Langini, Maike, Stühler, Kai, Remke, Marc, Perkins, Michael V., Bernardes, Gonçalo J. L., Chalker, Justin M.

Journal:

Year:

2019

File:

PDF, 7.01 MB

2019

33

Direct radiolabelling of proteins at cysteine using [18F]-fluorosugars

Boutureira, Omar, Bernardes, Gonçalo J. L., D'Hooge, François, Davis, Benjamin G.

Journal:

Chemical Communications

Year:

2011

Language:

english

File:

PDF, 1.35 MB

english, 2011

34

Methods for converting cysteine to dehydroalanine on peptides and proteins

Chalker, Justin M., Gunnoo, Smita B., Boutureira, Omar, Gerstberger, Stefanie C., Fernández-González, Marta, Bernardes, Gonçalo J. L., Griffin, Laura, Hailu, Hanna, Schofield, Christopher J., Davis, B

Journal:

Chemical Science

Year:

2011

Language:

english

File:

PDF, 1.07 MB

english, 2011

35

Bioorthogonal Decaging Reactions for Targeted Drug Activation

Davies, Sarah, Stenton, Benjamin J., Bernardes, Gonçalo J. L.

Journal:

CHIMIA International Journal for Chemistry

Year:

2018

Language:

english

File:

PDF, 247 KB

english, 2018

36

Urban Endocrine Disruptors Targeting Breast Cancer Proteins

Montes-Grajales, Diana, Bernardes, Gonçalo J.L., Olivero-Verbel, Jesus Tadeo

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 5.08 MB

english, 2015

37

An N -Acetyl Cysteine Ruthenium Tricarbonyl Conjugate Enables Simultaneous Release of CO and Ablation of Reactive Oxygen Species

Seixas, João D., Chaves-Ferreira, Miguel, Montes-Grajales, Diana, Gonçalves, Ana M., Marques, Ana R., Saraiva, Lígia M., Olivero-Verbel, Jesus, Romão, Carlos C., Bernardes, Gonçalo J. L.

Journal:

Chemistry - A European Journal

Year:

2015

Language:

english

File:

PDF, 1.06 MB

english, 2015

38

Antibody–drug conjugates: The missing link

Rodrigues, Tiago, Bernardes, Gonçalo J. L.

Journal:

Nature Chemistry

Year:

2016

Language:

english

File:

PDF, 371 KB

english, 2016

39

Bevacizumab for Refractory Gastrointestinal Bleeding in Rendu-Osler-Weber Disease

Bernardes, Carlos, Santos, Sara, Loureiro, Rafaela, Borges, Verónica, Ramos, Gonçalo

Journal:

GE Portuguese Journal of Gastroenterology

Year:

2018

File:

PDF, 3.63 MB

2018

40

Machine learning for target discovery in drug development

Rodrigues, Tiago, Bernardes, Gonçalo J.L.

Journal:

Current Opinion in Chemical Biology

Year:

2020

File:

PDF, 995 KB

2020

41

The Direct Formation of Glycosyl Thiols from Reducing Sugars Allows One-Pot Protein Glycoconjugation

Gonçalo J. L. Bernardes, David P. Gamblin, Benjamin G. Davis

Journal:

Angewandte Chemie International Edition

Year:

2006

Language:

english

File:

PDF, 267 KB

english, 2006

42

A Traceless Vascular-Targeting Antibody–Drug Conjugate for Cancer Therapy

Dr. Gonçalo J. L. Bernardes, Dr. Giulio Casi, Dr. Sabrina Trüssel, Isabelle Hartmann, Dr. Kathrin Schwager, Dr. Jörg Scheuermann, Prof. Dario Neri

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

43

A Traceless Vascular-Targeting Antibody–Drug Conjugate for Cancer Therapy

Dr. Gonçalo J. L. Bernardes, Dr. Giulio Casi, Dr. Sabrina Trüssel, Isabelle Hartmann, Dr. Kathrin Schwager, Dr. Jörg Scheuermann, Prof. Dario Neri

Journal:

Angewandte Chemie

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

44

Facile Conversion of Cysteine and Alkyl Cysteines to Dehydroalanine on Protein Surfaces: Versatile and Switchable Access to Functionalized Proteins

Bernardes, Gonçalo J. L., Chalker, Justin M., Errey, James C., Davis, Benjamin G.

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 662 KB

english, 2008

45

Collagen labelling with an azide-proline chemical reporter in live cells

Amgarten, Beatrice, Rajan, Rakesh, Martínez-Sáez, Nuria, Oliveira, Bruno L., Albuquerque, Inês S., Brooks, Roger A., Reid, David G., Duer, Melinda J., Bernardes, Gonçalo J. L.

Journal:

Chemical Communications

Year:

2015

Language:

english

File:

PDF, 1.80 MB

english, 2015

46

A Minimal, Unstrained S-Allyl Handle for Pre-Targeting Diels-Alder Bioorthogonal Labeling in Live Cells

Oliveira, Bruno L., Guo, Zijian, Boutureira, Omar, Guerreiro, Ana, Jiménez-Osés, Gonzalo, Bernardes, Gonçalo J. L.

Journal:

Angewandte Chemie

Year:

2016

Language:

english

File:

PDF, 2.02 MB

english, 2016

47

Hodgkin's Lymphoma in Crohn's Disease Treated with Infliximab

Carvalho, Diana, Russo, Pedro, Bernardes, Carlos, Saiote, Joana, Ramos, Gonçalo, Mascarenhas, Luís, Borges, Nuno, Ramos, Jaime

Journal:

GE Portuguese Journal of Gastroenterology

Year:

2017

Language:

english

File:

PDF, 569 KB

english, 2017

48

Norbornene probes for the study of cysteine oxidation

Alcock, Lisa J., Farrell, Kyle D., Akol, Mawey T., Jones, Gregory H., Tierney, Matthew M., Kramer, Holger B., Pukala, Tara L., Bernardes, Gonçalo J.L., Perkins, Michael V., Chalker, Justin M.

Journal:

Year:

2017

Language:

english

File:

PDF, 983 KB

english, 2017

49

Dissecting celastrol with machine learning to unveil dark pharmacology

Rodrigues, Tiago, de Almeida, Bernardo P., Barbosa-Morais, Nuno L., Bernardes, Gonçalo J. L.

Journal:

Chemical Communications

Year:

2019

File:

PDF, 508 KB

2019

50

Selenenylsulfide-Linked Homogeneous Glycopeptides and Glycoproteins: Synthesis of Human “Hepatic Se Metabolite A”

Dr. Omar Boutureira, Dr. Gonçalo J. L. Bernardes, Dr. Marta Fernández-González, Dr. Daniel C. Anthony, Prof. Benjamin G. Davis

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 660 KB

english, 2012

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